Figure 6 from Deuterium Metabolic Imaging Differentiates Glioblastoma Metabolic Subtypes and Detects Early Response to Chemoradiotherapy

Histologic assessment of tumor cell proliferation and cell death before and 24 hours after treatment. A-D, Representative sections of A11 and S2 tumors stained for Ki67 (A and B) and CC3 (C and D) pre- and posttreatment with chemoradiation. E-H, The percentage of Ki67-positive cells for A11 (E) and S2 (F) tumors and the percentage of CC3-positive cells for A11 (G) and S2 (H) tumors before and at 24 hours after completion of treatment. **, P < 0.01; ***, P < 0.001.