Supplementary Figure S3 from Efficacy and Safety of Glycosphingolipid SSEA-4 Targeting CAR-T Cells in an Ovarian Carcinoma Model

Supplementary Figure S3. IFN measurement and organ BLI of the short-term in vivo study. A. IFN quantification by ELISA in post-mortem mouse blood plasma. B. Representative BLI images of isolated organs from mice treated with PBS, NT-T, and CAR-T cells at the indicated T cell doses after 32 days. C. Organ BLI quantification. N=3 for control. N=5 for all groups, except N=2 for NT-T 1M, N=3 for CAR-T 1M, and N=4 NT-T 2M. Mean ± SD. One-way ANOVA with Tukey’s multiple comparison tests. (A) ***p=0.0005, ****p=0.0001. (C) *p=0.04, **p≤0.001 to PBS group. Not significant, n.s., differences were attributed to p≥0.05. (M=1x106).