Supplementary Figure S4. Carfilzomib overcomes primary ibrutinib resistance in vivo from B-Cell Lymphoma Patient-Derived Xenograft Models Enable Drug Discovery and Are a Platform for Personalized Therapy

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摘要
PT8 was clinically primary ibrutinib resistant. PT8-MCL PDX was generated and passaged. G3 mice were treated with vehicle control, IBN, and CFZ (P < 0.01, CFZ versus vehicle control or IBN, n = 5).
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