Supplmental Figures and Legends from ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas

This file provides illustration of supplemental experimental results and explanation of data presented. Supplemental Figure 1 Analysis of gene expression in CAG-A1Z transgenic mice. Supplemental Figure 2 Normal cerebellar development in Atoh1 transgenic animals. Supplemental Figure 3 Atoh1 over-expression enhances MB development and metastasis along the spinal cord in Ptch1+/- mice. Supplemental Figure 4 ATOH1-driven MB development and metastasis. Supplemental Figure 5 Analysis of gene expression in SHH MB from different mouse strains. Supplemental Figure 6 ATOH1-driven development and metastasis in AAP and LAP mice. Supplemental Figure 7 Analysis of gene expression in human MB. Supplemental Figure 8 Analysis of gene expression in MB from MAP animals.