Qualification of in Vitro Dissolution Absorption System 2 (IDAS2) with Caco-2 and MDCK Cell Monolayers: Dose Sensitivity Study Using BCS Class I and III Drugs

Haruki Higashino, Corey Francis Develin, Chie Higashino, Tyler Chae-Hoon Lim, Blair Jean Miezeiewski, Susan Lynn Rawa, Robert John Strab,Rachana Patel,Siddhartha Bhoopathy

Biological and Pharmaceutical Bulletin（2024）

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Key words

oral absorption,dissolution,Biopharmaceutics Classification System (BCS),oral product,Caco-2 cell,Madin-Darby canine kidney (MDCK) cell

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