Smart Wristband Monitoring: A Caregiver-Oriented Mobile Application for Tracking Cognitive Decline in Mild Cognitive Impairment Patients

Mild Cognitive Impairment (MCI) is the transitional phase between the typical expected memory problems related to age and the more serious decline of dementia. Therefore, monitoring progress from MCI to dementia is critical to slowing down this cognitive deterioration. Research shows that proper nutrition, routine brain, and physical exercise accompanied by proper care slow down the disease significantly. However, most of the patients do not perform these exercises regularly and their vital health data is not monitored properly, leaving patients most of the time with only basic care. In this study, for the first time to our knowledge, we aimed to develop a mobile application that will enable caregivers to continuously monitor the vital health, medication, activity, and location of the patients with MCI with a smart wristband while enabling them caregivers to track the progress of the disease by a machine learning model that tracks MMSE of the patient using speech. Based on our research so far, this caregiver-oriented approach with the ability to track progress of the disease using the convenience of a mobile application is a unique attempt in the field. Patient profile along with collected data is correlated with tracked MMSE scores of the patients to come up with recommendations and findings about the patients. Caregivers are relieved to be notified about critical health data thresholds, progress, and condition of their patients. ### Competing Interest Statement The authors have declared no competing interest. ### Clinical Trial NCT06417333 ### Funding Statement The author(s) received no specific funding for this work. ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: Non-interventional Ethics for Sports and Health Sciences- 2 Committee of Mugla Sitki Kocman University gave ethical approval for this work (protocol number:230086, October 18th, 2023). I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes Anonymous patient health data is going to be available in the application database after acceptance