A Native SEC-MS Workflow and Validation for Analyzing Drug-to-antibody Ratio and Drug Load Distribution in Cysteine-Linked Antibody-Drug Conjugates
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES(2024)
Key words
Antibody-drug conjugate,Drug-to-antibody ratio,Drug load distribution,Critical quality attribute,Native SEC-MS
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