Small-Molecule Disruptors of the Interaction Between Calcium- and Integrin-Binding Protein 1 and Integrin Αiibβ3 As Novel Antiplatelet Agents

Kalyan Golla,Adam Yasgar,Voddarahally N. Manjuprasanna,Meghna U. Naik,Bolormaa Baljinnyam,Alexey V. Zakharov,Sankalp Jain,Ganesha Rai,Ajit Jadhav,Anton Simeonov,Ulhas P. Naik

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE（2024）

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关键词

calcium- and integrin-binding protein 1 (CIB1),fluorescencepolarization (FP),inhibitors,high-throughput screening(HTS),classical quantitative structure-activity relationship(QSAR),protein-protein interactions (PPIs)

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