Phytosynthesis of [198Au]Au@SiO2 core–shell nanoparticles for potential radio-photothermal therapy

Ahsanal Fikri, Ligwina Dita Pertiwi, Alfian Mahardika Forentin, Dian Maya Sari,Sumandi Juliyanto,Amal Rezka Putra,Veronika Yulianti Susilo, Muhamad Basit Febrian,Herlan Setiawan,Anung Pujiyanto,Rien Ritawidya,Yoki Yulizar

Journal of Radioanalytical and Nuclear Chemistry（2024）

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摘要

[198Au]Au@SiO2 core–shell nanoparticles ([198Au]Au@SiO2 CSNPs) were synthesized using Persea americana Mill. seed (PAS) extract as a reducing agent. The synthesis involves amino-functionalized SiO2 core formation followed by shell formation with [198Au]Au seeds attachment and a reduction process. The resulting [198Au]Au@SiO2 CSNPs, sized at 188.96 nm, exhibited near-infrared (NIR) absorption at 750 nm and radiochemical purity of 99.91

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关键词

Core–shell,Silica nanoparticles,Gold nanoparticles,Phytosynthesis,Cancer cells,Radio-photothermal therapy

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