A mild Deprotection of Isopropylidene Ketals from 2-Deoxyglycosides Using AcOH/H2O/DME: An Efficient Regioselective Deprotection of Terminal Isopropylidene Ketals
Carbohydrate Research(2024)
摘要
This paper describes a mild and efficient catalytic deprotection method for isopropylidene ketals and benzylidene acetals using AcOH/H2O/DME(1,2-Dimethoxyethane). The method effectively removes ketal and acetal protecting groups from 2-deoxyglycosides which are prone to hydrolysis under acidic conditions. Moreover, it enables the selective removal of the terminal ketal over an internal one.
更多查看译文
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要