Tepotinib-induced hand-foot skin reaction

Tepotinib may cause hand-foot skin reactions with keratotic changes. When such changes are observed in the hands or toes after starting tepotinib treatment, its side effects should be considered, and corticosteroid ointment or withdrawal of tepotinib should be considered if necessary. Herein, we report a case of tepotinib-induced hand-foot skin reaction (HFSR) with keratotic changes. image