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Efficacy study of facial products enriched with probiotics/prebiotics & cannabinoids

Vasileia Xagorari, Zoi Tiligada,Panagoula Pavlou, Chalikias Miltiadis,Spyridon Papageorgiou,Athanasia Varvaresou

Epitheorese Klinikes Farmakologias kai Farmakokinetikes – Greek Edition(2024)

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Abstract
With the increase in interest for natural innovative skin care products, an effort was made in our laboratory to study the beneficial effects of cannabinoids and prebiotics/probiotics on the skin. Through efficacy studies, the contribution of the specific active substances to improving the health and appearance of the skin was investigated. The present research offers important data creating new perspectives for the improvement of skin care with natural ingredients. The research was carried out on 13 healthy volunteers from the ages of 24 - 53. Two products (Cream and Serum) with the active substances under study and placebo ones were used. The cosmetic products were applied externally to the skin, twice a day for 30 days. The methods used were: a) self-assessment questionnaire, and b) non-intrusive biophysical parameters. Specifically, skin elasticity (Cutometer dual MPA 580), skin microtopography (Skin Visioscan VC 98), transepidermal water loss (MPA5-Tewameter) and hydration of the keratin layer (MPA5-Corneometer CM) were measured 825). Based on the findings, the main conclusions of the research are summarized, highlighting the effectiveness of the products in improving the quality of the skin.
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