Exploring Perspectives of Older Adults on Digital Brain Health Platform with Natural Language Processing: A Pilot Cohort Study (Preprint)

BACKGROUND Although digital technology represents a growing field aiming to revolutionize early Alzheimer's disease (AD) risk prediction and monitoring, the perspectives of older adults on an integrated digital brain health platform have not been investigated. OBJECTIVE This study aims to understand the perspectives of older adults on a digital brain health platform by conducting semi-structured interviews and analyzing their transcriptions by natural language processing (NLP). METHODS The study included 28 participants from the Boston University Alzheimer’s Disease Research Center (BU ADRC), all of whom engaged with a digital brain health platform over an initial assessment period of 14 days. Semi-structured interviews were conducted to collect data on participants' experiences with the digital brain health platform. The transcripts generated from these interviews were analyzed using NLP techniques. The frequency of positive and negative terms was evaluated through word count analysis. A sentiment analysis was used to measure the emotional tone and subjective perceptions of the participants towards the digital platform. RESULTS Word count analysis revealed a generally positive sentiment towards the digital platform, with "like", "well", and "good" being the most frequently mentioned positive terms. However, terms such as "problem" and "hard" indicated certain challenges faced by participants. Sentiment analysis showed a slightly positive attitude with a median polarity score of 0.13 on a scale from -1 (completely negative) to 1 (completely positive), and a median subjectivity score of 0.51, ranging from 0 (completely objective) to 1 (completely subjective). These results suggested an overall positive attitude among the study cohort. CONCLUSIONS The study highlights the importance of understanding older adults' attitudes toward digital health platforms amidst the comprehensive evolution of the digitalization era. Future research should focus on refining digital solutions to meet the specific needs of older adults, fostering a more personalized approach to brain health. CLINICALTRIAL