Long term exposure to PM<sub>2.5</sub> chemical components associated with prevalence of cardiovascular diseases in China
The Innovation Medicine(2024)
Ambient fine particulate matter pollution (PM2.5) has been widely associated with cardiovascular disease (CVD). However, less is known about the contribution of different chemical components of PM2.5 to CVD using a nationally representative sample in China.
A nationally representative sample of older adults was recruited from 31 provinces, municipalities, or autonomous regions of China by the fourth national Urban and Rural Elderly Population Survey in 2015. We estimated the annual average concentrations of PM2.5 and its five dust-free chemical components (black carbon [BC], organic matter [OM], sulphate [
A total of 220,425 participants with a mean age of 69.73 years, 52.24% females, and 6.08% minor ethnicity were included in the study, of which 55,837 (25.3%) reported having CVD. An interquartile range (IQR) increment in annual PM2.5 chemical components was associated with significantly elevated risk of CVD prevalence. The odds ratios were 1.254 (95% CI: 1.235-1.275, IQR: 7.11 ?g/m3) for
Our study suggests that long-term exposure to PM2.5 chemical components could increase the risk of CVD prevalence. Future air pollution guidelines target reducing specific PM2.5 chemical components may help alleviate the burden of CVD.
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