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Pediatric-type low-grade gliomas in adolescents and young adults—challenges and emerging paradigms

Julie Bennett,Kee Kiat Yeo,Uri Tabori,Cynthia Hawkins,Mary Jane Lim-Fat

Child's Nervous System（2024）

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Abstract
Pediatric-type low-grade glioma (PLGG) encompasses a heterogeneous group of WHO grade 1 or 2 tumors and is the most common central nervous system tumor found in children. PLGG extends beyond pediatrics, into adolescents and young adults (AYA, ages 15–40). PLGG represents 25
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Key words
Adolescents and young adults,Pediatric-type low-grade glioma,RAS/MAPK alterations,Targeted therapy,Molecular testing
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