The Effect of Ten Weeks of Moderate Intensity Continuous Training on Serum Levels of Adipokines Related to Energy Homeostasis (Asprosin and Leptin) in Obese Women.

Aims: Asprosin and leptin are two adipokines related to appetite and metabolic disorders. The present study aimed to determine the effect of ten weeks of moderate-intensity continuous training on body mass index and serum levels of leptin, asprosin, insulin, and fasting blood sugar in sedentary obese women. Materials and Methods: In the current semi-experimental research that was conducted on obese women in 2023 in Tehran, Iran, 24 sedentary obese women were purposefully selected and randomly divided into two groups of 12, including training and control groups. In the training group, sports intervention was performed for ten weeks and three sessions per week, and during the research, the control group did not receive sports intervention. To evaluate the investigated variables on two occasions, 24 hours before the start of training interventions and 72 hours after the last training session, fasting blood was taken. For statistical analysis, dependent t-tests and covariance analysis were used. Statistical analysis was done with SPSS 26 software and significance level (p<0.05). Findings: The average age and body mass index in the training group were 41.33±2.74 years and 32.46±2.53 kg/m2, and in the control group, was 41.0±3.19 years and 32.21±3.48 kg/m2, respectively. After the intervention period, a significant decrease in body mass index (0.951 kg/m2), asprosin (0.116 ng/ml), leptin (2.816 ng/ml), and insulin (14.34 units/l) was observed in the training group compared to the control group (p<0.05). However, no significant difference was observed in FBS (p>0.05). Conclusion: According to the results, moderate-intensity continuous training with asprosin and fasting leptin modulation has positive effects on the metabolic status of sedentary obese women.