Effects of chronic exposure to a high fat diet, nutritive or non-nutritive sweeteners on hypothalamic-pituitary-adrenal (HPA) and -gonadal (HPG) axes of male Sprague-Dawley rats

Yiyuan Zhang, Chunyun Luo, Puxin Huang, Lu Chen, Yufang Ma, Hong Ding

European Journal of Nutrition(2024)

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摘要
Diet-related factors are of great significance in the regulation of hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-gonad (HPG) axes. In this study, we aimed to investigate the effects of chronic exposure to a high fat diet (HFD), fructose or sucralose on the endocrine functions. Male, Sprague-Dawley rats received a normal chow diet, HFD, 10
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关键词
Sweeteners,High fat diet,Endocrine system,Hypothalamic-pituitary-adrenal axis,Hypothalamic-pituitary-gonad axis
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