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Protective Effects of β-Blockers on Bone in Older Adults with Dementia

Khiem Khuc,Jude des Bordes,Abayomi Ogunwale,Maria-Bernadette Madel, Catherine Ambrose,Paul Schulz,Florent Elefteriou,Ann Schwartz,Nahid J. Rianon

Calcified Tissue International（2024）

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Abstract
Increased β-adrenergic receptor activity has been hypothesized to cause bone loss in those with dementia. We investigated the effect of long-term β-blocker use on rate of bone loss in older adults with dementia. We used a linear mixed-effects model to estimate the relationship between long-term β-blocker use and rate of bone loss in participants from the Health Aging and Body Composition study. Records of 1198 participants were analyzed, 44.7
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Key words
β-blockers,Bone loss,Older adults,Dementia,Health ABC
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