Arrhythmic Risk in Young Women with Mitral Valve Prolapse: Keep Your Eyes Open but Don't Jump at Every Shadow.

Graphical AbstractOpen in new tabDownload slideLeft panel: Mitral valve prolapse is frequent in the general population, but SCD as one cause of cardiac mortality related to MVP during the perinatal period is very rare. Right panel: Each of the 18 women included in the study is represented in one line. In the first column, an alphanumeric code indicates the institution which has included the patient. The majority of women presented with an out-of-hospital cardiac arrest while not taking anti-arrhythmic drugs, half of them during the perinatal period. Following the first episode, all were prescribed anti-arrhythmic drugs. Recurrences while on beta-blockers were very sporadic and mainly occurred outside the perinatal period. Of note, VT/VF recurrence occurred in only one of eight patients while on flecainide. Abbreviations: MVP, mitral valve prolapse; SCD, sudden cardiac death; VT, ventricular tachycardia; VF, ventricular fibrillation