Discovery of novel 1,2,4-triazole tethered β-hydroxy sulfides as bacterial tyrosinase inhibitors: synthesis and biophysical evaluation through in vitro and in silico approaches

This study reports the bacterial tyrosinase inhibiting potency of a series of novel 1,2,4-triazole-tethered β-hydroxy sulfide scaffolds 11(a–h), synthesized in good yields (69–90%).