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Analysis of a diffusive two-strain malaria model with the carrying capacity of the environment for mosquitoes ⋆

Infectious Disease Modelling(2024)

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Abstract
We propose a malaria model involving the sensitive and resistant strains, which is described by reaction-diffusion equations. The model reflects the scenario that the vector and host populations disperse with distinct diffusion rates, susceptible individuals or vectors cannot be infected by both strains simultaneously, and the vector population satisfies the logistic growth. Our main purpose is to get a threshold type result on the model, especially the interaction effect of the two strains in the presence of spatial structure. To solve this issue, the basic reproduction number (BRN) and invasion reproduction number (IRN) of each strain (i = 1 and 2 are for the sensitive and resistant strains, respectively) are defined. Furthermore, we investigate the influence of the diffusion rates of populations and vectors on BRNs and IRNs.
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Key words
Threshold dynamics,Two-strain malaria model,Competition and coexistence,Reproduction number
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