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Unveiling the Significance of Impurity Profiling: A Comprehensive Exploration of Novel Analytical Techniques for Ensuring Quality and Safety in Herbal Formulations

European Journal of Medicinal Chemistry Reports(2024)

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Abstract
Herbal Phytoconstituents also known as traditional medicines are considered to be harmless with no side effects. Herbal medicines have a global market value of 60 billion and have become increasingly popular in Western communities. Recent studies indicate that many herbal formulations in the market today have not been tested for quality and efficacy. The research outcomes suggest a proper quality check is necessary with novel analytical techniques to ensure product's safety. Thus, the impurities and their limits in herbal formulations should be examined as per pharmacopeial standards guidelines. The present review article emphasizes the importance of impurity profiling in herbal formulations and its significant role in natural product quality control. This article also suggests utilizing simple, precise and accurate, analytical methods to eliminate impurities, adulteration and combined synthetic chemicals in herbal products. In conclusion, implementing stricter regulations and creating public awareness about natural product safety measures can eradicate these adulterations since herbal formulations are in high demand in the commercial market after COVID-19.
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Key words
Adulteration,Impurities,Indian pharmacopeial standards,Phytoconstituents,Quality control,Synthetic chemicals
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