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Discovery of LC-MI-3: A Potent and Orally Bioavailable Degrader of Interleukin-1 Receptor-Associated Kinase 4 for the Treatment of Inflammatory Diseases

Lingfeng Chen,Ruixiang Luo,Lin Ma,Ying Xu, Jiaqi Cao, Zheng Jiang, Shiyan Chen, Xiaohao Huang,Mingwan Zhang,Lei Zheng,Yawen Zhang,Lina Yin,Jie Yu,Xiaochun Zheng,Lulu Zheng,Ping Huang,Guang Liang

Journal of Medicinal Chemistry（2024）

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