Eculizumab for Paroxysmal Nocturnal Hemoglobinuria: Two Cases of Successful Pregnancy Outcomes

Jovanka Ilic, Borislava Pujic, Branislava Jakovljevic,Borivoj Sekulic,Danijela Agic,Amir El Farra, Branimir Micanovic, Tihomir Vejnovic, Ivana Urosevic,Aleksandar Savic

Clinical case reports（2024）

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摘要

Paroxysmal nocturnal hemoglobinuria is a rare disease with the incidence ranging from 0.08 to 0.57 per 100,000 person-years. Up to 25% of cases in women are detected during pregnancy. We report two cases of successful pregnancy outcomes in patients treated with eculizumab, pointing out the importance of interdisciplinary approach in these high-risk pregnancies.

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关键词

eculizumab,paroxysmal nocturnal hemoglobinuria,PNH,pregnancy

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