In Vitro Antibacterial Activity of Sulbactam-Durlobactam in Combination with Other Antimicrobial Agents Against Acinetobacter baumannii-calcoaceticus Complex

Combinations of the β-lactam/β-lactamase inhibitor sulbactam-durlobactam and seventeen antimicrobial agents were tested against strains of Acinetobacter baumannii in checkerboard assays. Most combinations resulted in indifference with no instances of antagonism. These results suggest sulbactam-durlobactam antibacterial activity against A. baumannii is unlikely to be affected if co-dosed with other antimicrobial agents.