Synthesis, crystal structure and anticancer activity of the complex chlorido(η2-ethylene)(quinolin-8-olato-κ2 N,O)platinum(II) by experimental and theoretical methods

Nguyen Thi Thanh Chi,Ngo Tuan Cuong, Tran Thu Trang,Pham Van Thong, Nguyen Thi Bang Linh, Nguyen Thi Khanh Ly,Luc Van Meervelt, S.-L. Zheng

Acta Crystallographica Section E Crystallographic Communications（2024）

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摘要

In the complex [Pt(C9H6NO)Cl(C2H4)], ethylene coordinates with PtII in the η2 manner and in the trans position compared to the coordinating N atom. The in vitro anticancer activity was investigated and DFT calculations were performed to support its anticancer activity.

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platinum(II) complex,crystal structure,anticancer activity,8-hydroxyquinoline,DFT

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Synthesis, crystal structure and anti­cancer activity of the complex chlorido­(η2-ethyl­ene)(quinolin-8-olato-κ2 N,O)platinum(II) by experimental and theoretical methods

Synthesis, crystal structure and anticancer activity of the complex chlorido(η2-ethylene)(quinolin-8-olato-κ2 N,O)platinum(II) by experimental and theoretical methods