Evidence of SARS-CoV-2 convergent evolution in immunosuppressed patients treated with antiviral therapies

The factors contributing to the accelerated convergent evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are not fully understood. Unraveling the contribution of viral replication in immunocompromised patients is important for the early detection of novel mutations and developing approaches to limit COVID-19. We deep sequenced SARS-CoV-2 RNA from 192 patients (64