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Effect of Cocoa Consumption on Postprandial Blood Pressure in Older Adults with Untreated Hypertension: A Randomized Crossover Clinical Trial

Food Frontiers(2024)

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摘要
AbstractCocoa powder is an important dietary source of flavanols that modulate elevated blood pressure (BP). This study aimed to investigate the acute effects of cocoa beverage co‐consumption with a high‐fat‐high‐salt meal (HFHSM) on postprandial systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate in older adults living with uncontrolled hypertension. The study was a randomized crossover trial and involved older adults (aged 52.50 ± 9.36 years) (n = 28) living with hypertension. Participants, following an overnight fast, consumed either an HFHSM and cocoa beverage comprising 15 g cocoa powder in 250 mL water (HFHSM + CB; intervention) or HFHSM and 250 mL water (HFHSM + W; control). Resting SBP, DBP, and the heart rate of participants were measured at baseline (−5 min and 0 min) and 15, 30, 45, 60, 90, and 120 min following the consumption of either HFHSM + CB or HFHSM + W using an automated BP monitor. Repeated measures linear mixed model was used to compare the effect of cocoa beverage and water on postprandial outcomes over a 2‐h period. A significant reduction (−3.8 ± 0.6 mmHg, p < .05) in resting SBP was observed postprandially following the intake of the HFHSM + CB over the 120‐min period compared to the HFHSM + W. The effect was more prominent during the 90‐ and 120‐min time points of the trial duration. No significant change in the DBP and heart rate following the consumption of HFHSM + CB compared to the HFHSM + W was observed. Cocoa beverage co‐consumption with HFHSM improved postprandial SBP in older adults living with hypertension.
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关键词
cocoa beverage,diastolic blood pressure,heart rate,hypertension,systolic blood pressure
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