Granulomatous Meningoencephalitis and Blindness Associated with Mycobacterium Tuberculosis Complex Infection in a Senile Female Chimpanzee (pan Troglodytes)
Journal of medical primatology(2024)
Abstract
A 40-year old female chimpanzee (Pan troglodytes) developed hyporexia, weight loss, followed by progressive and complete blindness. Tomography demonstrated an intracranial mass in the rostroventral brain involving the optic chiasm, with a presumptive diagnosis of neoplasm. However, histopathology revealed a granulomatous meningoencephalitis, and tissue samples tested positive for Mycobacterium tuberculosis.
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Key words
blindness,encephalitis,meningitis,mycobacteriosis,tuberculosis
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