Cabotegravir and rilpivirine long acting injectables in a pregnant woman living with HIV.

Lena van der Wekken-Pas, Fabian Weiss, Charlotte Simon-Zuber, Rena Sebisch, Carmen Wiese,Elisabeth van Leeuwen,David Burger,Angela Colbers

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2024）

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摘要

This case report describes bimonthly LAI CAB/RPV prior to and throughout pregnancy. CAB concentration was comparable to non-pregnant individuals, RPV was 70-75% lower. No virologic failure orvertical transmission occurred. Despite placental transfer, no congenital malformations were noted. Bimonthly CAB/RPV LAI may not be suitable for pregnant women and monitoring of exposed infants is warranted.

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