A phased array ultrasonic transducer linear sinusoidal driving system for ultrasound neuromodulation

Ultrasound application has been proven to be a promising noninvasive neuromodulation technique due to the high penetration depth, and high focusing properties. Compared to single-element ultrasonic transducers, phased array transducers have the advantages of adjustable focusing targets and higher focusing accuracy, making them more suitable for transcranial neuromodulation technology. However, there is currently limited research on phased array ultrasonic transducer linear sinusoidal driving systems for precise transcranial neuromodulation. This paper develops a new type of phased array linear driving system, using sine wave as input wave, and designs a new OCL-AB power amplifier circuit based on the Output CapitorLess circuit (OCL) and Class-AB circuit. Furthermore, the dedicated input signal generator and focusing control module are designed and combined with the excitation circuit to form a balanced transformerless (BTL) structure to further boost the output voltage. The experimental results show that the 16-channel prototype of the system can meet various parameter requirements for neural regulation under standard mode ±60 V and BTL mode ±120 V output voltage at 100KHz-1 MHz, and has smaller focusing spot and higher frequency accuracy.