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Epidemiological trends and susceptibility patterns of bloodstream infections caused by Enterococcus spp. in six German university hospitals: a prospectively evaluated multicentre cohort study from 2016 to 2020 of the R-Net study group

Daniel Hornuss,Siri Göpel,Sarah V. Walker,David Tobys,Georg Häcker,Harald Seifert,Paul G. Higgins,Kyriaki Xanthopoulou,Beryl Primrose Gladstone,Chiara Cattaneo,Alexander Mischnik,Anna M. Rohde,Can Imirzalioglu,Janina Trauth,Moritz Fritzenwanker,Jane Falgenhauer,Petra Gastmeier,Michael Behnke,Evelyn Kramme,Nadja Käding,Jan Rupp,Silke Peter,Kristina Schmauder,Simone Eisenbeis,Winfried V. Kern,Evelina Tacconelli,Siegbert Rieg

Infection（2024）

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Abstract
To analyse recent epidemiological trends of bloodstream infections (BSI) caused by Enterococcus spp. In adult patients admitted to tertiary care centres in Germany. Epidemiological data from the multicentre R-NET study was analysed. Patients presenting with E. faecium or E. faecalis in blood cultures in six German tertiary care university hospitals between October 2016 and June 2020 were prospectively evaluated. In vancomycin-resistant enterococci (VRE), the presence of vanA/vanB was confirmed via molecular methods. In the 4-year study period, 3001 patients with BSI due to Enterococcus spp. were identified. E. faecium was detected in 1830 patients (61
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Key words
Enterococcus,VRE,Bloodstream infection,E. faecium,E. faecalis
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