Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019.

Kentaro Tohma, Michael Landivar,Lauren A Ford-Siltz, Kelsey A Pilewski,Joseph A Kendra,Sandra Niendorf,Gabriel I Parra

Emerging infectious diseases（2024）

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摘要

Norovirus is a major cause of acute gastroenteritis; GII.4 is the predominant strain in humans. Recently, 2 new GII.4 variants, Hong Kong 2019 and San Francisco 2017, were reported. Characterization using GII.4 monoclonal antibodies and serum demonstrated different antigenic profiles for the new variants compared with historical variants.

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关键词

viruses,norovirus,acute gastroenteritis,GII.4 variants,Hong Kong 2019 variant,San Francisco 2017 variant

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