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Detection of OXA-181 Carbapenemase in Shigella flexneri.

Ghulam Dhabaan,Hassan Jamal, Danielle Ouellette, Sarah Alexander, Karen Arane,Aaron Campigotto,Manal Tadros,Pierre-Philippe Piché-Renaud

Emerging infectious diseases（2024）

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Abstract
We report the detection of OXA-181 carbapenemase in an azithromycin-resistant Shigella spp. bacteria in an immunocompromised patient. The emergence of OXA-181 in Shigella spp. bacteria raises concerns about the global dissemination of carbapenem resistance in Enterobacterales and its implications for the treatment of infections caused by Shigella bacteria.
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Key words
Shigella flexneri,carbapenemase,OXA-48,OXA-48-like,OXA-181,bacteria
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