Discovery of dibenzylbutane lignan LCA derivatives as potent anti-inflammatory agents

Zhen Wang, Juan Zhang, Conghao Gai, Jing Wang,Xiaobin Zhuo, Yan Song,Yan Zou, Peichao Zhang,Gui-Ge Hou,Qingguo Meng,Qingjie Zhao,Xiaoyun Chai

RSC Medicinal Chemistry（2024）

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摘要

LCA, a dibenzylbutane lignan extracted from the roots of traditional medicinal plant Litsea cubeba (Lour.) Pers., has demonstrated promising anti-inflammatory activity and low cytotoxicity. In this study, a series of...

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