The highly selective and sensitive fluorescence probe for detection of copper (II) ions and its bioimaging in vitro and vivo
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy(2024)
Abstract
We designed and developed the probe W-3 for detection of Cu2+. The results showed probe can selectively detect Cu2+, accompanied by noticeable color change. The probe can detect the Cu2+ in water samples and drinks based on absorption detection. In addition, the combination of portable test paper and the smartphone platform obtained great convenience for on-site and visual detection of Cu2+, with satisfactory sensitivity and reliability. More importantly, the fluorescence probe W-3 can be used for the detection of Cu2+ in cells and mice. Therefore, the W-3 provided potential chemical tools for detecting Cu2+ in vitro and vivo.
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Key words
Probe,Fluorescence,Cu2+,Visual recognition,Bioimaging
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