Triclonal Gammopathy in Multiple Myeloma with Bleeding Diathesis: A Case Report

Gammopathies have clinical and diagnostic significance for lymphoproliferative disorders and plasma cell dyscrasias such as multiple myeloma which is distinguished by the malignant growth of a plasma cell clone that generates monoclonal immunoglobulin. A 70-year old patient was evaluated for recurrent epistaxis and bleeding per rectum along with severe anemia in the past two months. A general physical examination revealed pallor. Blood tests showed pancytopenia. Hemogram, biochemical investigations, SPE, Serum-free light chain assay, Immunofixation electrophoresis, Bone marrow aspiration cytology Immunophenotyping, and flow cytometry. Immunofixation electrophoresis showed triclonal gammopathy IgM Kappa, IgG Kappa, and IgA Lambda and SPE quantitation of M band—5.6 gm