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Family history and gastric cancer incidence and mortality in Asia: a pooled analysis of more than half a million participants

Dan Huang,Minkyo Song,Sarah Krull Abe,Md. Shafiur Rahman,Md. Rashedul Islam,Eiko Saito,Katherine De la Torre,Norie Sawada,Akiko Tamakoshi,Xiao-Ou Shu,Hui Cai,Atsushi Hozawa,Seiki Kanemura,Jeongseon Kim,Yu Chen,Hidemi Ito,Yumi Sugawara,Sue K. Park,Myung-Hee Shin,Mayo Hirabayashi,Takashi Kimura,Yu-Tang Gao,Wanqing Wen,Isao Oze,Aesun Shin,Yoon-Ok Ahn,Habibul Ahsan,Paolo Boffetta,Kee Seng Chia,Keitaro Matsuo,You-Lin Qiao,Nathaniel Rothman,Wei Zheng,Manami Inoue,Daehee Kang

Gastric Cancer（2024）

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Abstract
The family history of gastric cancer holds important implications for cancer surveillance and prevention, yet existing evidence predominantly comes from case–control studies. We aimed to investigate the association between family history of gastric cancer and gastric cancer risk overall and by various subtypes in Asians in a prospective study. We included 12 prospective cohorts with 550,508 participants in the Asia Cohort Consortium. Cox proportional hazard regression was used to estimate study-specific adjusted hazard ratios (HRs) and 95
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Key words
Gastric cancer,Family history,Incidence,Mortality,Asian
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