Systematic Characterization of Multi-Omics Landscape Between Gut Microbial Metabolites and GPCRome in Alzheimer’s Disease

Yunguang Qiu,Yuan Hou,Dhruv Gohel,Yadi Zhou,Jielin Xu,Marina Bykova,Yuxin Yang,James B. Leverenz,Andrew A. Pieper,Ruth Nussinov,Jessica Z. K. Caldwell,J. Mark Brown,Feixiong Cheng

CELL REPORTS（2024）

Cited 2|Views25

Key words

Alzheimer's disease,gut microbiota,gut microbial metabolite,G-protein-coupled receptors,orphan GPCR,machine learning,AlphaFold2,metabolite-protein interaction,Mendelian randomization,multi-omics

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