The efficacy and safety of short-course radiotherapy followed by sequential chemotherapy and Cadonilimab for locally advanced rectal cancer: a protocol of a phase II study

Tongzhen Xu,Lingling Feng,Wenjue Zhang, Haoyue Li,Huiying Ma,Muyasha Abulimiti, Yutong Tan, Feiyan Deng,Wenting Huang,Shuangmei Zou, Wenyan Kang,Liming Jiang,Ying Wang, Chen Hu,Yinggang Chen,Haitao Zhou, Yuan Tang,Jing Jin

BMC Cancer（2024）

Cited 0|Views24

No score

Abstract

For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before surgery, was commonly recommended as the standard treatment. However, the risk of distant metastasis at 3 years remained higher than 20

Translated text

Key words

Locally advanced rectal cancer,Bispecific antibody immunotherapy,Short-course radiotherapy,Total neoadjuvant therapy,Complete response

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined