Current Status of Cardiac CT for Nuclear Medicine Professionals: Coronary Artery Disease Evaluation

With advances in computed tomography (CT) technology over the past two decades, cardiac CT has become a noninvasive diagnostic tool for morphological evaluation of coronary artery disease (CAD) caused by atherosclerotic plaques and stenosis and serves as a “gatekeeper” before invasive coronary angiography. Additionally, cardiac CT stress perfusion and CT-derived fractional flow reserve can be used to assess the hemodynamic significance of coronary artery stenosis. Delayed enhancement CT can detect and localize myocardial infarction and assess myocardial viability. Currently, cardiac CT serves as a potential “one-stop-shop” imaging modality for the comprehensive assessment of patients with suspected or known CAD by providing analysis of coronary anatomy, functional significance, and characterization of left ventricular myocardium in a single session. It is crucial for nuclear medicine professionals to be aware of the current capability of cardiac CT and its ability to perform comprehensive and accurate nuclear cardiac imaging studies, which are essential for functional assessment of CAD.