Utility of Cellular Measurements of Non-Specific Endocytosis to Assess the Target-Independent Clearance of Monoclonal Antibodies

Mark A. Bryniarski,Md Tariqul Haque Tuhin, Carolyn D. Shomin, Fatemeh Nasrollahi, Eunkyung Clare Ko,Marcus Soto, Kyu Chung, Carrie Poon-Andersen,Ronya Primack, Diana Wong, Esperanza Ojeda,John Chung,Kevin D. Cook,Kip P. Conner

Journal of Pharmaceutical Sciences（2024）

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关键词

Non-specific endocytosis,Therapeutic antibodies,Pharmacokinetics,Target-independent clearance

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