Novel PIKfyve/Tubulin Dual-target Inhibitor as a Promising Therapeutic Strategy for B-cell Acute Lymphoblastic Leukemia

Current Medical Science（2024）

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摘要

In B-cell acute lymphoblastic leukemia (B-ALL), current intensive chemotherapies for adult patients fail to achieve durable responses in more than 50

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关键词

B-cell acute lymphoblastic leukemia,dual-target inhibitor,NF-κB,c-Myc,PI3K/AKT,p53

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