In Vitro Evaluation and Characterization of Double Emulsion Based on Polyvinylpyrrolidone/Agarose/ZIF-8 Hydrogel Nanocomposite Platform for Quercetin Delivery to Breast Cancer Cells

Quercetin (QC) is a matchable option for cancer remedy, lessens the issues relevant to low solvability, and its quick release has become urgent. This research used a newfound nanocarrier based on a hydrogel nanocomposite, including polyvinylpyrrolidone (PVP), agarose (Aga), and ZIF-8 nanoparticles to load QC. Being of nanocomposite ingredients was authenticated by FTIR and XRD analysis. The surface correlation of the nanocomposite and stability of the nanocarrier produced was approved by FESEM images, Zeta, and DLS analysis, consecutively. With ZIF-8, drug loading is 47.50