Recent Advances in the Use of 2-Aminobenzyl Alcohols in the Synthesis of Quinolines, Quinazolines and Other N-Heterocycles

N-Heterocyclic compounds, in particular, quinolines and quinazolines are frequently used in medicinal chemistry. Therefore, the direct and clean synthesis of these valuable scaffolds has been a great interest for many years. 2-Aminobenzyl alcohols as an alternative reactant instead of unstable and expensive 2-aminobenzaldehydes can be used in the construction of N-fused heterocycles including quinolines, quinazolines, oxazines, thiazines, selenazines, imidazoles, diazepines, etc. In this review article, we have discussed recent developments in the use of 2-aminobenzyl alcohols in the synthesis of diverse heterocycles. image