Pathology of Squamous Cell Carcinoma of the Penis: Back to Square One
Urologic Clinics of North America(2024)
摘要
The landscape of squamous cell carcinoma of the penis (SCC-P) has undergone a significant transformation since the new World Health Organization classification of genitourinary cancers and recent European Association of Urology/American Association of Clinical Oncology guidelines. These changes emphasize the necessity to categorize SCC-P into 2 groups based on its association with human papillomavirus (HPV) infection. This shift has major implications, considering that prior knowledge was derived from a mix of both groups. Given the distinct prognosis, treatment options, and staging systems observed for HPV-associated tumors in other body areas, the question now arises: will similar patterns emerge for SCC-P?
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关键词
Penile cancer etiology,Penile cancer pathology,Human papillomavirus,p16,Carcinogenesis,Penile intraepithelial neoplasia
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