Synthetic Modifications of Therapeutically Relevant Pre-assembled Cucurbitacins: Synthetic Strategies and Structure-Activity Relationships
JOURNAL OF MOLECULAR STRUCTURE(2024)
Key words
Cucurbitacins,Cucurbitane glycosides,Semisynthetic derivatives,Total synthesis,Anti-cancer activity,Toxicity,CIEA NSCLC,Hepatocellular cancer,EGFR,MTOR,STAT,MAPK,IGF2BP1,ROS,Apoptosis,Cell cycle arrest
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