Metal-free photoinduced denitrogenative alkylation of vinyl azides with alkyl radicals toward ketones

A simple and general approach for the synthesis of ketones via a metal-free denitrogenative alkylation of vinyl azides with redox-active esters or Katritzky salts under visible light irradiation is described herein. This method features a broad substrate scope and good functional group compatibility including valuable transformation of bioactive molecules, thereby providing a sustainable and alternative technique for ketone preparation compared to the present strategies. A metal-free method for the synthesis of ketones via a visible-light induced denitrogenative alkylation of vinyl azides with alkyl radicals is presented.