Oligonucleotide Purification by Ion Exchange Chromatography: A Step-by-Step Guide to Process Understanding, Modeling, and Simulation

Kilian Kobl,Lucrece Nicoud, Edouard Nicoud,Anna Watson,John Andrews, Edward A. Wilkinson,Muhid Shahid,Christopher Mckay,Benjamin I. Andrews, Batool Ahmed Omer, Olga Narducci, Edward Masson, Suzanne H. Davies, Tobias Vandermeersch

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2024）

Cited 2|Views10

Key words

oligonucleotides,process simulation,ion exchangechromatography,purification,mechanistic modeling

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