Ambient Temperature Metal-Free Thiomethylation of Chloroheteroarenes and Chloropurines.
Chemistry, an Asian journal(2024)
Abstract
Herein, we report an in-situ mild and metal-free protocol for thiomethylation of heteroarenes in high yields. The thiomethylation of various chloropurines, nucleosides, and chloroheteroarenes has been accomplished offering easy access to agrochemicals and synthetic molecules useful for drug discovery.
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